ENDOCRINE PHARMACOLOGY
- Diabetes mellitus - Human Mixtard or H.Mixtard (Insulin),lantus,
- calcium - Tablet Shelcal(calcium),calciumsandoz(osteoporosis).
- thyroid harmones - L-thyroxine(Thyroid harmone subsitute).
- ENDORCINE SYSTEM ANTONYM
- Corticosteroids: adverse side effects CUSHINGS BAD MD:
- Cataracts
- Up all night (sleep disturbances)
- Suppression of HPA axis
- Hypertension/ buffalo Hump
- Infections
- Necrosis (avascular)
- Gain weight
- Striae
- Bone loss (osteoporosis)
- Acne
- Diabetes
- Myopathy, moon faces
- Depression and emotional changes
- Oral contraceptives: side effects
- CONTRACEPTIVES:
- Cholestatic jaundice x bile secretion
- Oedema (corneal)
- Nasal congestion x ischemia
- Thyroid dysfunction
- Raised BP x hypotension
- Acne/ Alopecia/ Anaemia x increased red blood cells
- Cerebrovascular disease
- Elevated blood sugar x hypoglycemia
- Porphyria/ Pigmentation/ Pancreatitis
- Thromboembolism
- Intracranial hypertension x hypotension
- Vomiting (progesterone only)
- Erythema nodosum/ Extrapyramidal effects
- Sensitivity to light
- steroids is The 5 S’s — sick, sad, sex, salt and sugar
- Oral contraceptive complications: warning signs OR severe complications or oral birth control pills
- ACHES:Abdominal pain
- Chest pain
- Headache (severe)
- Eye (blurred vision)
- K+ increasing agents K-BANK:
- K-sparing diuretic
- Beta blocker
- ACEI
- NSAID
- Ksupplement
- PANCREATIC ENZYME REPLACEMENT - starts with pancrea
- ADH MEDS - ends in pressin
- THYROID MEDS - starts with thyro, thy, thro
- CALCIUM REGULATORS - ends in dronate (hypocalcemia), tonin hypercalcemia)
- SULFONYLUREAS - ends in ide, amide, zide, ride
- NON-SULFONYLUREAS - ends in glinide, glitazone
- -ide; oral hypoglycemics
- -mide ;diuretic
- -zide; diuretic
- -pril ;ACE inhibitor
- -sone ;steroids
- -statin ;cholesterol
- -pril = ACE inhibitor
- -statin = cholesterol lowering agent
- -sartan = angiotensin receptor blocker
- -sone = glucocorticoid
- -lone, pred- = corticosteroid
- -trophin = Pituitary Hormone
Discussion